Stiff-person syndrome

The singer repeatedly postponed performances in the past year because of severe muscle spasms. In a tearful Instagram post, she revealed she has been ...

Celine Dion is coping with a serious disorder that makes people unable to talk or walk -- and as a result, she's forced to postpone her European tour once ...

"Unfortunately, the spasms affect every aspect of my daily life, sometimes causing difficulties when I walk and not allowing me to use my vocal cords to sing ...

In an emotional Instagram video post, the singer opened up about her rare neurological disorder—forcing her to postpone her Europe tour.

“This is my focus, and I’m doing everything that I can to recuperate.” “I have a great team of doctors working alongside me to help me get better and my precious children who are supporting me and giving me hope,” she says. It’s what I’ve done all my life, and it’s what I love to do the most.” Dion was diagnosed with stiff person syndrome that affects “something like one in a million people,” she says to her fans. “I have to admit, it’s been a struggle,” she says in the video message. In a tearful message on her Instagram, the “My Heart Will Go On” artist says she has to postpone her Europe tour dates set for 2023.

Celine Dion just revealed she's been diagnosed with stiff person syndrome. Here's what you need to know about the disorder.

“The handful of people I’ve seen with stiff person syndrome have not been particularly progressive—it’s not universally progressive,” he says. There was a study that looked into using the drug rituximab, but it “proved ineffective” in treating people with stiff person syndrome, NINDS says. Medications can improve symptoms of stiff person syndrome but won’t cure the condition, NINDS says. (People with stiff person syndrome have higher-than-usual levels of GAD, an antibody that works against an important neurotransmitter in the brain. The spinal cord has been damaged and the symptoms of spinal cord injury need to be addressed using medicines that reduce spasms.” With the right treatment, symptoms are usually controlled, NINDS says. That can mean using medications like benzodiazepines or baclofen to treat muscle stiffness and spasms, along with anti-seizure medications, according to the Cleveland Clinic. “The immune system is attacking the spinal cord and that attack needs to be stopped using immune suppression. “We know how to stop the progression of this disease with immune suppression,” Dr. “Recently, I’ve been diagnosed with a very rare neurological condition called stiff person syndrome, which affects something like one in a million people,” she shared in the post’s video. Because it’s so rare, stiff person syndrome can be misdiagnosed as Parkinson’s disease, multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia, NINDS says. The condition is very rare—about one out of every one million people have been diagnosed with it, the Cleveland Clinic says, but twice as many women have stiff person syndrome as men.

“Unfortunately, these spasms affect every aspect of my daily life, sometimes causing difficulties when I walk and not allowing me to use my vocal cords to sing ...

“This means a lot to me,” Dion concluded her message tearfully. “This is my focus.” “But I have to admit it’s been a struggle.” “Unfortunately, these spasms affect every aspect of my daily life, sometimes causing difficulties when I walk and not allowing me to use my vocal cords to sing the way I’m used to.” “Spasms can generate enough force to fracture bone.” “I miss seeing all of you, being on the stage, performing for you.

Researchers call it a neurological disorder with features of an autoimmune disease. It causes muscle stiffness in a person's torso and limbs, and a heightened ...

“A lot of people are able to make recovery to the point that their condition is stable. They can continue to live fairly mobile (lives),” he notes, adding that it’s possible Dion can recover to the point where she is performing again. Physical, occupational and aqua therapy is also an important part of the treatment, according to “Those muscles are prone to spasm, or tightening up, and I’m sure it can affect the way that she sings and performs,” Mijatovic says. Since the symptoms mimic other conditions, it can be difficult to diagnose. Desimir Mijatovic, a pain medicine specialist with the Cleveland Clinic in Ohio. “If those muscles aren’t working properly, that can make it very difficult.” “Unfortunately, these spasms affect every aspect of my daily life, sometimes causing difficulties when I walk and not allowing me to use my vocal cords to sing the way I’m used to. Researchers call it a neurological disorder with features of an autoimmune disease. [National Institute of Neurological Disorders and Stroke](https://www.ninds.nih.gov/health-information/disorders/stiff-person-syndrome). It causes muscle stiffness in a person’s torso and limbs, and a heightened sensitivity to noise, touch and emotional stress, which can set off painful muscle spasms, according to the [Celine Dion opens up](https://www.today.com/health/celine-dion-reveals-rare-neurological-disease-stiff-person-syndrome-rcna60708) about the health problems forcing her to postpone and cancel some of her performances, she’s putting the spotlight on stiff person syndrome.

Celine Dion's diagnosis with stiff-person syndrome has called attention to the rare disorder, which causes muscle spams and rigidity in the torso and limbs.

Stiff person syndrome is a rare neurological condition that can take years to diagnose and tailor treatment.

The condition impacts the brain and spinal cord, and Dion says it has affected her vocal cords and interfered with her ability to sing.

“I always give a hundred percent when I do my shows, but my condition is not allowing me to give you that right now.” In addition, some people may take anti-seizure medicines, anti-inflammatories, or [corticosteroids](/corticosteroids/guide/) to reduce pain. But the progression of symptoms isn’t linear, and the severity and frequency of symptoms vary from one patient to the next. But she did say her path to recovery has been challenging. GABA regulates motor neurons that control movement throughout the body, and when there’s not enough of this protein, the nervous system can shift to overdrive and interfere with normal movement. Treatment instead focuses on symptom management and minimizing disability related to the condition. People tend to go through repeated cycles where the condition worsens and then improves, according to NORD. [National Organization for Rare Disorders (NORD)](https://rarediseases.org/rare-diseases/stiff-person-syndrome/). “As you know, I’ve always been an open book, and I wasn’t ready to say anything before, but I’m ready now,” Dion said in the video. The condition is also more common in people with [autoimmune diseases](https://www.everydayhealth.com/autoimmune-diseases/all-articles/) such as [rheumatoid arthritis](/rheumatoid-arthritis/guide/) and [lupus](/lupus/). “Recently, I’ve been diagnosed with a very rare neurological disorder called the stiff-person syndrome, which affects something like one in a million people,” Dion continued. [benzodiazepines](https://www.everydayhealth.com/sleep-disorders/xanax-valium-benzodiazepines-prescribed-for-sleep-disorders-raise-overdose-risk/) — such as [diazepam](/drugs/diazepam) and [clonazepam](/drugs/clonazepam) — or the muscle relaxant [baclofen](/drugs/baclofen) to reduce muscle stiffness and spasms, according to the [Cleveland Clinic](https://my.clevelandclinic.org/health/articles/6076-stiff-person-syndrome).

Stiff-person syndrome, which has forced Canadian superstar singer Celine Dion to postpone her European tour, is a very rare neurological condition that ...

[said on Instagram](https://www.instagram.com/p/Cl5xJY1AjAO/?hl=en). The name has since been changed – women, in fact, make up a majority of cases. [according to NORD](https://rarediseases.org/rare-diseases/stiff-person-syndrome/). [added](https://www.instagram.com/p/Cl5xJY1AjAO/?hl=en). [wrote in the journal Neurology](https://n.neurology.org/content/99/23_Supplement_2/S12). [according to](https://rarediseases.org/rare-diseases/stiff-person-syndrome/) the US National Organization for Rare Disorders (NORD).

Celine Dion canceled her upcoming tour after being diagnosed with this rare neurological condition. Here's what we know.

Because of how rare it is, stiff person syndrome is typically diagnosed by first ruling out other, more common conditions. The treatment for the condition is often a patchwork of medication and non-medication interventions, Dr. Diagnosing the condition takes a combination of tools, Dr. The rigidity and spasming can be treated with muscle relaxers and Botox injections. The presence of the chronic pain can also lead some patients to [develop anxiety](https://link.springer.com/article/10.1007/s11940-009-0013-9), depression and [phobias](https://n.neurology.org/content/64/11/1961.short) of going outside or trying new activities. There is no cure for stiff person syndrome, so doctors focus on symptom and pain management. The muscle spasms can be triggered by a variety of environmental factors, such as The exact cause of the condition is not clear, but “the immune system is involved,” said Dr. Stiff person syndrome often begins with stiffness in the torso and abdomen, which can then spread to the legs, arms and face, Dr. The syndrome is difficult to diagnose, Dr. [have been tied to](https://www.yalemedicine.org/conditions/stiff-person-syndrome) a slight increase in risk for developing the syndrome, Dr. It was first coined in the 1920s (as “stiff man syndrome”) after doctors

In an emotional, five-minute Instagram video, Dion told fans: 'I've been dealing with problems with my health for a long time'.

For diagnosis of stiff-person syndrome, the antibody amount against GAD65 must be very high. Most SPS patients have antibodies to glutamic acid decarboxylase or GAD65, an enzyme that produces the important inhibitory brain chemical GABA. "And when the pain occurs, it's very debilitating, no matter what position, he added. The muscle spasms are what neurologists call "stimulus sensitive" and can be provoked by a sudden noise, light touch or even emotional distress. Lin said the main effect is on quality of life. Diagnosis also often relies on a blood test that measures the GAD antibody. Other treatments involve using muscle relaxants, anti-convulsants and pain medications for those experiencing pain. In other words, when the nervous system becomes overly excited, it can send too many signals to the muscles, causing them to stiffen or spasm. It usually has an autoimmune component, and in some cases, it can be progressive and painful, experts say. There is no clear mechanism for why these antibodies are generated, Lin said. Those who have symptoms that are not well-controlled may need to use a walker or wheelchair to keep from falling or injuring themselves. It's very painful," said Kunal Desai, assistant professor of neurology at Yale University.

Celine Dion took to Instagram to share that she has an incurable rare neurological disorder called stiff-person syndrome. Her tour has been postponed until ...

Celine Dion claims the disease has harmed her vocal chords and has hampered her ability to sing. Know more about this rare neurological condition.

[Celine](/topic/celine)stated in her emotional video, this very rare condition affects one in a million people and damages the body's central nervous system. An emotional Celine [Dion](/topic/dion)stated in a five-minute video released on Instagram in French and English that she has been suffering from health concerns "for a long time”. Celine said that she had neurological issues in her everyday life that prevented her from using her vocal chords like she used to.

"While we're still learning about this rare condition, we now know that this is what has been causing all of the spasms that I've been having," the singer ...

[muscle](https://indianexpress.com/article/lifestyle/fitness/how-to-build-muscle-tips-fitness-7784059/) spasms are the norm and superimposed upon baseline muscle stiffness. [brain ](https://indianexpress.com/article/lifestyle/health/lifestyle-changes-to-build-the-healthiest-brain-8099833/)and spinal cord. [muscle](https://indianexpress.com/article/lifestyle/health/muscle-strength-mass-loss-ageing-health-8222525/) stiffness and spasm that preferentially affects axial (back and abdominal) muscles, neurological experts noted. 70 per cent of patients with GAD antibodies have [diabetes ](https://indianexpress.com/article/lifestyle/health/5-lifestyle-tips-risk-of-diabetes-weight-physical-activity-sugar-8298388/)mellitus as a comorbidity. In patients with paraneoplastic Stiff Person Syndrome, identification and eradication of the underlying malignancy can alleviate symptoms. It is commonly associated with affective symptoms such as anxiety, phobias and The disorder has left her with difficulties in [walking ](https://indianexpress.com/article/lifestyle/fitness/walking-exercise-strength-training-yoga-rujuta-diwekar-8118751/)and singing due to which she will be unable to take part in planned shows in the UK and Europe next year. “In the classical form of the disease, the initial symptom is typically painful muscle stiffness in the lumbosacral and abdominal regions. But symptoms can also include a person having greater sensitivity to noise, touch, and emotional distress,” Dr Gupta said. It frequently affects [women with a median onset of 35 to 40 years of age](https://indianexpress.com/article/lifestyle/health/lifestyle-changes-women-40s-expert-tips-health-7981725/),” Dr Mohan Krishna J, Consultant Neurologist, Yashoda Hospitals, [Hyderabad](https://indianexpress.com/section/cities/hyderabad/) said. According to experts, this syndrome can manifest itself in many ways. “The malignancies associated with stiff-person syndrome are

Canadian singer Celine Dion announced that she has a neurological disease called stiff person syndrome, which has led to her cancelling European tour plans ...

FRIDAY, Dec. 9, 2022 (HealthDay News) -- Stiff-person syndrome: Superstar singer Celine Dion announced Thursday that she is living with this rare neurological ...